Apr 01, 2026 - There is more than one way for triple-negative breast cancer to become resistant to therapy
About 50% of triple-negative breast cancer (TNBC) patients develop resistance to therapy. When resistance arises, tumors are more likely to come back after the original treatment, significantly reducing the chances of survival. Researchers at Baylor College of Medicine have discovered that there is more than one way TNBC can become immune to therapy. Their study, published in the Journal of Clinical Investigation, reveals two mutually exclusive mechanisms that can give TNBC the ability to survive therapy. The findings have implications for treatment. Knowing ahead of time which resistance mechanism a patient’s tumor is likely to implement can guide treatment decisions to prevent or reduce resistance. (BCM "From The Labs" - read more)