Liqun Immunity

Fatty acids promote immune suppression and therapy resistance in triple negative breast cancer

Fatty acids promote immune suppression and therapy resistance in triple negative breast cancer

Apr 02, 2025 - Fatty acids promote immune suppression and therapy resistance in triple negative breast cancer

A new study published in the journal Immunity reveals a mechanism that allows triple negative breast cancer (TNBC) to develop resistance to therapy. Researchers at Baylor College of Medicine showed that lipid accumulation in tumor cells and nearby immune cells promotes immune suppression, but disrupting lipid formulation reverses treatment resistance and the immunosuppressive microenvironment.  (BCM News - read more)